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Apogee and Spyre founder launches another autoimmune biotech, and it's got...

Amid an action-packed Thursday, another biotech launched to take on the ever-popular landscape of autoimmune drug development. And the new Boston-area biotech comes from a repeat creator: Paragon...

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In Japan, sales of Eisai and Biogen's Alzheimer's drug begin to accelerate

Biogen and Eisai’s Alzheimer’s drug Leqembi is off to a slow start in the US. But it’s big in Japan. On Friday, Eisai revealed in an investor presentation that Japanese revenue accounted for 1.5...

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Exclusive: Devoted Health raises $112M, plots insurance markets expansion

(This story is from our new Health Tech newsletter. If you’d like to sign up, just click here.) Devoted Health just nabbed another $112 million in venture funding to fuel its push into seven new...

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Iron chelator therapy unexpectedly worsened Alzheimer’s disease in clinical...

PHILADELPHIA — Among the many mysteries of Alzheimer’s disease is the role that iron plays. The metal is vital for transporting oxygen in the blood and producing energy from mitochondria, but some...

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Massachusetts' plan for $1B in life science investment stalls in state...

Massachusetts Gov. Maura Healey’s proposal to invest another $1 billion in life sciences over the next 10 years has been imperiled after failing to make it through the state’s legislative body before...

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Doses of Lilly's blockbuster GLP-1 in shortage have been pulled from FDA...

Doses of Eli Lilly’s blockbuster weight loss and diabetes drugs that were listed as in short supply no longer are, according to the FDA’s database that tracks drugs in limited supply. The agency’s...

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Advisory committee votes in favor of Zevra Therapeutics' rare genetic disease...

A panel of outside advisors to the FDA voted 11-5 in favor of Zevra Therapeutics’ drug for a rare genetic condition called Niemann-Pick disease type C, saying that it is effective based on current...

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Eisai’s new Leqembi data; Jim Wilson’s next move; Roivant dealmaker’s payday;...

Welcome back to Endpoints Weekly, your review of the week’s top biopharma headlines. Want this in your inbox every Saturday morning? Current Endpoints readers can visit their reader profile to add...

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Bayer details 3,200 job cuts so far, spotlights ‘momentum’ in pharma pipeline

Bayer is “on track” to realize the €2 billion in cost savings it’s aiming for in 2026, executives say, even as they report another quarter of “modest” performance across its crop science,...

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A new Apple Tree Partners biotech launches with $55M to make ‘pan-variant’...

Red Queen Therapeutics is emerging from stealth with $55 million from venture capital group Apple Tree Partners, and plans to develop treatments for a swathe of viral infections including Covid-19 and...

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Merck enlists partner Daiichi Sankyo to develop T cell engager from Harpoon...

Daiichi Sankyo is paying Merck $170 million upfront to snag joint development and commercialization rights to a Phase 1/2 T cell engager that the New Jersey pharma giant got in its Harpoon acquisition...

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Japanese government grants Shinobi $59M for cell therapy development

Cell therapy biotech Shinobi Therapeutics has pulled in $59 million in funding from a Japanese government grant. The pharma company also expanded its Series A round from last year. The Japanese Agency...

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Exclusive: TCG, DCVC and Lux back new autoimmune biotech from Kallyope...

A stealth biotech from repeat collaborators has assembled the latest industry megaround. New York-based NILO Therapeutics has put together a $101 million Series A, Tim Kutzkey, a board member and...

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Genentech partners with cash-strapped Sangamo on epigenetic Alzheimer’s therapy

An experimental Alzheimer’s drug and its designer are getting a second chance. On Tuesday, Sangamo announced it had partnered with Genentech to develop an epigenetic repressor to prevent the production...

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Hims takes steps to lock up drug supply for its booming weight loss business

(This story is from our new Health Tech newsletter. If you’d like to sign up, just click here.)   Hims CEO Andrew Dudum did his best Monday to reassure investors that the digital health startup’s...

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Arie Belldegrun and team unveil $600M life sciences credit firm amid...

A new $600-plus million credit firm was unveiled Tuesday morning from Arie Belldegrun and other well-known life sciences names. Rather than create another venture capital firm, the Kite Pharma founder...

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Exclusive: Covid and epidemic threat biotech Aerium Therapeutics closes after...

Aerium Therapeutics has ceased operations, ending its mission to bring to market new antibodies to protect immunocompromised people from Covid-19, develop highly sought-after long Covid treatments and...

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BioCryst culls Factor D inhibitor; Elevation Oncology’s stock plummets

Plus, news about Tenax Therapeutics: BioCryst discontinues Factor D inhibitor: This is after finding that “clinical activity observed was less than other therapies on the market.” The company tried to...

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Eisai picks SEED Therapeutics for molecular glue deal worth as much as $1.5B

Eisai is paying SEED Therapeutics an undisclosed amount upfront in a deal worth up to $1.5 billion to develop new ‘molecular glue’-based therapies for neurodegenerative diseases and cancer. The...

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Bicycle Therapeutics focuses pipeline and streamlines leadership team

Bicycle Therapeutics spelled out its pipeline priorities on Tuesday, adding that it will be looking for collaborators for its immune-oncology pipeline. It is also narrowing its executive team. The...

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