Talc claimants file class action suit accusing J&J of fraud over bankruptcy...
As Johnson & Johnson attempts to settle tens of thousands of talc lawsuits, a group of five plaintiffs filed new litigation on Tuesday accusing the company of efforts to “hinder, delay, and...
View Article#ASCO24 abstracts are out, with results from Nimbus, Nuvation, Pfizer and J&J
Abstracts for the American Society of Clinical Oncology are out, with new data from Pfizer’s ADC, Nimbus Therapeutics’ immuno-oncology drug, Nuvation Bio’s ROS1 inhibitor and new data from J&J in...
View Article#ASCO24: Nuvation Bio shares pivotal China data for cancer drug from AnHeart...
Nuvation Bio showcased longer-term Phase 2 data around the next-gen ROS1 inhibitor it hopes will give Pfizer and Bristol Myers Squibb a run for their money. In a study conducted in China, taletrectinib...
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#ASCO24: Pfizer shares the ADC data that convinced it to start a Phase 3 lung...
When Pfizer laid out the ambitious vision for its new oncology division in February, it announced that it was taking the antibody-drug conjugate sigvotatug vedotin directly from Phase 1 to Phase 3. Now...
View Article#ASCO24: Nimbus shares new data, 'grand' hopes for HPK1 cancer drug, after...
Just over a year ago, Nimbus Therapeutics closed one of the biggest single-drug deals in biotech, selling its TYK2 inhibitor to Takeda for $4 billion upfront. Now, CEO Jeb Keiper is planning the...
View Article#ASCO24: Merck, Kelun trumpet Phase 3 breast cancer data for anti-TROP2 ADC
Merck and Kelun-Biotech revealed Phase 3 breast cancer data for the lead antibody-drug conjugate in their potentially $12 billion partnership. In a Phase 3 trial for locally recurrent or metastatic...
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#ASCO24: J&J plans for capped, flexible dosing after four patient deaths in...
An experimental prostate cancer drug developed by Johnson & Johnson that uses a rare radioactive particle called actinium-225 led to three patients seeing their tumors shrink substantially, but...
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Idorsia’s Jean-Paul Clozel retires as CEO, plots next steps; CRISPR...
Jean-Paul Clozel → Jean-Paul Clozel is ready to pass the torch at his Actelion follow-up Idorsia, but he doesn’t want to walk away from the company altogether. Clozel will retire as CEO on June 13, and...
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Zealand touts safety of new ‘double-G’ drug despite modest weight loss in...
Zealand Pharma appears to have taken a small step forward with a candidate that targets both GLP-1 and GLP-2, an approach that aims to ease side effects seen in many obesity drugs. In the...
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Novo's semaglutide hits secondary endpoints in Ph3 kidney disease trial,...
Novo Nordisk’s semaglutide cut the risk of major cardiovascular events and death from multiple causes in a Phase 3 study involving patients with type 2 diabetes and chronic kidney disease, building the...
View ArticleHI-Bio outlines data that sparked $1.15B Biogen buyout
Days after getting acquired by Biogen, Human Immunology Biosciences revealed Phase 2 data that helped seal the deal. In the trial, which looked at the anti-CD38 antibody felzartamab’s potential to...
View Article#ASCO24: A roundup of the latest data from Merus, MorphoSys and others
Read on for news about Immunocore, Arcus, CG Oncology, Genmab, Merck and GSK: Merus stock spikes on data in head and neck squamous cell carcinoma: The biotech’s shares $MRUS rose more than 20% on...
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Verastem's stock takes a hit after sharing updated filing plans in ovarian...
For a moment, Verastem Oncology looked like one of the early winners of the American Society of Clinical Oncology’s annual meeting. The company’s shares $VSTM were trading up over 50% after hours based...
View ArticleLilly budgets additional $5.3B for tirzepatide API factory in Indiana
Eli Lilly is further boosting manufacturing in its home state of Indiana. The company said it is allocating an additional $5.3 billion into its budget to build an active pharmaceutical ingredient (API)...
View ArticleFDA denies Ipsen's citizen petition for blockbuster drug Somatuline
US drug regulators have turned down Ipsen’s effort to slow down generic competition for its blockbuster drug Somatuline Depot, which is used to slow the growth of some tumors as well as for the rare...
View ArticlePublic Citizen sues FDA over citizen petition on SSRI sexual side effects...
The FDA should require drugmakers to warn patients of potential long-term sexual side effects from a certain class of antidepressants, the consumer advocacy group Public Citizen argued in a new lawsuit...
View ArticleStartup Hims has long-term plans for custom weight loss shots
Digital health company Hims & Hers plans to offer custom versions of wildly popular weight loss shots even after supply shortages resolve, according to an investor report this week. Hims’ stock...
View ArticleFDA advisory committee says risks of Novo Nordisk’s once-weekly insulin...
An FDA advisory committee on Friday voted not to recommend Novo Nordisk’s once-weekly insulin injection in type 1 diabetes patients. Novo has pitched its candidate as a more convenient alternative to...
View ArticlePfizer's $1.5B cuts; Biogen's $1.15B buyout; AstraZeneca's $80B ambition; RNA...
Welcome back to Endpoints Weekly, your review of the week’s top biopharma headlines. Want this in your inbox every Saturday morning? Current Endpoints readers can visit their reader profile to add...
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Novartis to seek approvals in two rare kidney diseases after positive Phase 3...
Novartis is building out its rare kidney disease portfolio with two batches of Phase 3 data at the European Renal Association conference, touting positive results for an investigational drug in IgA...
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